The discovery, in March 2003, of the mutation responsible for Hutchinson-Gilford Progeria Syndrome (a rare genetic disease that causes children to age very prematurely) led the Marseille-based research team to develop the combination of two molecules acting effectively in synergy against this disease.
One of the major factors of cellular ageing is the production of a "toxic" protein: progerin.
This protein builds up in cell nuclei, particularly in stem cells, prevents them from functioning normally and causes them to progressively disappear.
Stem cells ensure that the body's tissues are constantly renewed, and in particular that of the skin. Their progressive disappearance is therefore one of the causes of skin ageing.
Neo Stem offers a unique combination of two active ingredients from the pharmaceutical field, never yet used in cosmetics: Omega Statine and Z-Dronate.
The combined action of Omega Statine and Z-Dronate, slows down the production of progerin and stimulates the renewal of cells (including stem cells), for lastingly revitalized skin.
These active ingredients enable all of the skin's cells to resume an activity of cell division, repair of DNA and production: the fibroblasts (dermal cells) produce proteins such as elastin, collagen and large molecules (like hyaluronic acid), which structure the dermis and give it its volume. The keratinocytes (epidermal cells) and subcutaneous fat cells are also involved.
Our active ingredients, present in Neo Stem, prevent the progressive disappearance of the stem cells essential to cell renewal, and improve the functioning of cells in the three layers of the skin: epidermis, dermis and hypodermis, together with the functioning of cells in the walls of blood vessels providing them with nutrients.
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